After studying History, Anthropology and Sociology (EHESS) with Jean-Louis Fabiani and Clarisse Herrenschmidt, Sophie Marino completed a doctorate in Information and Communication Sciences under the supervision of Daniel Jacobi. She also completed a 3rd cycle in European studies at Sciences Po Paris.

She taught at the University of Avignon as a lecturer and then as a temporary teaching and research associate, was head of research at the Ecole Supérieure d'Art d'Avignon and has also worked as a museographer. Sophie Marino also teaches in the Cycle pluridisciplinaire d'Études Supérieures at Paris Sciences Lettres University.

Her research focuses on the recomposition and transmission of knowledge. Her fields of reflection include museum enunciation and exhibition narratives, and the relationship between art and ethnographic discourse.